Wilson and Gisvold's Textbook of Organic Medicinal and PharmaceuticalChemistry

Abstract

Wilson and Gisvold's Textbook of Organic Medicinal and Pharmaceutical Chemistry is a
comprehensive textbook that covers the fundamental principles of organic chemistry and their
application to the design, synthesis, and development of pharmaceuticals. Part I provides a
foundation in the basics of organic chemistry, including structure and bonding, functional
groups, and stereochemistry. It also introduces the concept of medicinal chemistry and the
different types of pharmaceuticals that are available. Part II covers the major functional classes
of organic medicinal compounds, such as analgesics, anti-inflammatory drugs, antibiotics, and
antidepressants. For each functional class, the book discusses the mechanisms of action,
structure-activity relationships, and clinical applications of the drugs. Part III focuses on the drug
discovery and development process. It begins with a discussion of target identification and
validation, followed by chapters on lead discovery, lead optimization, and preclinical and clinical
development. The book concludes with a chapter on the regulatory approval process and the
marketing of new drugs. The comprehensive textbook that covers the fundamental principles of
organic chemistry, biochemistry, and biology that underlie the discipline of medicinal chemistry.
It also includes information on the properties, mode of action, therapeutic applications, and
limitations of various pharmaceutical agents. The book is organized by pharmaceutical and
therapeutic classes, providing a bridge between the basic sciences and clinical practice. The
textbook is written in a clear and concise style, and it is well-organized and easy to navigate. It is
also profusely illustrated with diagrams, tables, and figures.